{"id":53595,"date":"2025-03-28T08:33:54","date_gmt":"2025-03-28T00:33:54","guid":{"rendered":"https:\/\/www.chemhui.com\/?p=53595"},"modified":"2025-03-19T18:36:53","modified_gmt":"2025-03-19T10:36:53","slug":"%e3%80%90nat-catal-%e3%80%91%e7%bb%93%e6%9e%84%e4%b8%8e%e6%9c%ba%e5%88%b6%ef%bc%9a%e8%a1%80%e7%ba%a2%e7%b4%a0%e4%be%9d%e8%b5%96%e6%80%a7%e5%93%8c%e5%97%aa%e9%85%b8%e5%90%88%e9%85%b6%e5%82%ac%e5%8c%96","status":"publish","type":"post","link":"http:\/\/www.chemhui.com\/%e3%80%90nat-catal-%e3%80%91%e7%bb%93%e6%9e%84%e4%b8%8e%e6%9c%ba%e5%88%b6%ef%bc%9a%e8%a1%80%e7%ba%a2%e7%b4%a0%e4%be%9d%e8%b5%96%e6%80%a7%e5%93%8c%e5%97%aa%e9%85%b8%e5%90%88%e9%85%b6%e5%82%ac%e5%8c%96\/","title":{"rendered":"\u3010Nat. Catal.\u3011\u7ed3\u6784\u4e0e\u673a\u5236\uff1a\u8840\u7ea2\u7d20\u4f9d\u8d56\u6027\u54cc\u55ea\u9178\u5408\u9176\u50ac\u5316\u5f62\u6210\u6c2e-\u6c2e\u952e"},"content":{"rendered":"<section><img decoding=\"async\" title=\"1\" src=\"https:\/\/10110.seohost.cn\/storage\/10110\/article\/20250319\/1742380540204490.png\" alt=\"1\" \/><\/section>\n<p>\u542b\u6709\u6c2e-\u6c2e\uff08N\u2013N\uff09\u952e\u7684\u5206\u5b50\u6db5\u76d6\u4e86\u591a\u79cd\u5b98\u80fd\u56e2\uff0c\u5305\u62ec\u80bc\u3001\u91cd\u6c2e\u5316\u5408\u7269\u3001<span class=\"\">\u5421\u5511<\/span>\u548cN-\u4e9a\u785d\u57fa\u5316\u5408\u7269\u3002\u542bN\u2013N\u7684\u5206\u5b50\u662f\u6c2e\u5faa\u73af\u4e2d\u7684\u5173\u952e\u4e2d\u95f4\u4f53\uff0c\u5e76\u5b58\u5728\u4e8e\u91cd\u8981\u7684\u5408\u6210\u836f\u7269\u4e2d\uff0c\u5982\u745e\u5fb7\u897f\u97e6\u548c<span class=\"\">\u7f2c\u6c99\u5766<\/span>\u3002\u6b64\u5916\uff0c\u5df2\u53d1\u73b0\u6570\u767e\u79cd\u542b\u6709N\u2013N\u952e\u7684\u7279\u6b8a\u5929\u7136\u4ee3\u8c22\u7269\uff0c\u6700\u8fd1\u7684\u7814\u7a76\u63ed\u793a\u4e86\u8fd9\u4e9b\u542bN\u2013N\u952e\u5206\u5b50\u7684\u76f8\u5e94\u751f\u7269\u5408\u6210\u9014\u5f84\uff0c\u5c55\u73b0\u4e86\u591a\u79cd\u591a\u6837\u7684\u751f\u7269\u5408\u6210\u7b56\u7565\uff0c\u8fd9\u4e9b\u7b56\u7565\u7ecf\u8fc7\u8fdb\u5316\u4ee5\u5b9e\u73b0N\u2013N\u952e\u7684\u5f62\u6210\u3002\u7136\u800c\uff0c\u5728\u67d0\u4e9b\u751f\u7269\u5408\u6210\u9014\u5f84\u4e2d\uff0c\u5bf9\u76f4\u63a5\u5f62\u6210N(<em>sp<sup>3<\/sup><\/em>)\u2013N(<em>sp<sup>3<\/sup><\/em>)\u63d0\u51fa\u4e86\u4e00\u4e2a\u96be\u9898\uff1a\u4e24\u4e2a\u901a\u5e38\u5177\u6709\u4eb2\u6838\u6027\u7684\u539f\u5b50\u5fc5\u987b\u7ed3\u5408\u3002\u4e3a\u4e86\u76f4\u63a5\u5f62\u6210N(<em>sp<sup>3<\/sup><\/em>)\u2013N(<em>sp<sup>3<\/sup><\/em>)\u952e\uff0c\u76f8\u5173\u7684\u9176\u5fc5\u987b\u9006\u8f6c\u5176\u4e2d\u4e00\u4e2a\u6c2e\u539f\u5b50\u7684\u5178\u578b\u4eb2\u6838\u6027\u3002\u76ee\u524d\uff0c\u5173\u4e8e\u514b\u670dN\u2013N\u952e\u5f62\u6210\u8fd9\u4e00\u57fa\u672c\u969c\u788d\u7684\u9176\u4fc3\u673a\u5236\uff0c\u77e5\u4e4b\u751a\u5c11\u3002<\/p>\n<section><img decoding=\"async\" title=\"2\" src=\"https:\/\/10110.seohost.cn\/storage\/10110\/article\/20250319\/1742380558946104.png\" alt=\"2\" \/><\/section>\n<p>\u56fe\u7247\u6765\u6e90\uff1aNat. Catal.<\/p>\n<p>\u6709\u9274\u4e8e\u6b64\uff0cThe University of British Columbia\u7684Katherine S. Ryan\u4e0e\u5176\u5408\u4f5c\u8005\u62a5\u9053\u4e86\u4e00\u79cd\u8840\u7ea2\u7d20\u4f9d\u8d56\u6027\u9176PipS\u7684\u7ed3\u6784\uff0c\u5176\u5728N<sup>5<\/sup>-OH-L-\u9e1f\u6c28\u9178\u7684\u73af\u5316\u8fc7\u7a0b\u4e2d\u50ac\u5316N\u2013N\u952e\u7684\u5f62\u6210\uff0c\u751f\u6210L-\u54cc\u55ea\u9178\u3002\u8fd9\u9879\u7814\u7a76\u63ed\u793a\u4e86Lys-Thr\u4e8c\u5143\u4f53\u5728\u50ac\u5316\u65e9\u671f\u7684\u4f5c\u7528\uff0c\u5e76\u8868\u660ePipS\u4ee5\u5e95\u7269\u7279\u5f02\u6027\u7684\u65b9\u5f0f\u50ac\u5316N\u2013N\u952e\u7684\u5f62\u6210\u6216\u4e9a\u80fa\u57fa\u56e2\u7684\u5f62\u6210\uff0c\u8fd9\u53ef\u80fd\u6e90\u4e8e\u4e00\u4e2a\u5171\u4eab\u7684\u6c2e\u70ef\u4e2d\u95f4\u4f53\uff0c\u8be5\u4e2d\u95f4\u4f53\u6709\u6548\u5730\u9006\u8f6c\u4e86\u7f9f\u80fa\u6c2e\u7684\u4eb2\u6838\u6027\u3002\u8fd9\u9879\u7814\u7a76\u6269\u5c55\u4e86\u5bf9\u9176\u4fc3N\u2013N\u952e\u5f62\u6210\u7684\u8ba4\u8bc6\uff0c\u5e76\u9610\u660e\u4e86\u8840\u7ea2\u7d20\u8f85\u56e0\u5b50\u7684\u50ac\u5316\u591a\u529f\u80fd\u6027\uff0c\u4e3a\u57fa\u56e0\u7f16\u7801\u7684N\u2013N\u952e\u5f62\u6210\u751f\u7269\u50ac\u5316\u5242\u94fa\u5e73\u4e86\u9053\u8def\u3002<\/p>\n<section><img decoding=\"async\" title=\"3\" src=\"https:\/\/10110.seohost.cn\/storage\/10110\/article\/20250319\/1742380579690472.png\" alt=\"3\" \/>\u200b<\/section>\n<p>\u56fe\u7247\u6765\u6e90\uff1aNat. Catal.<\/p>\n<p>\u539f\u6587\u6807\u9898\uff1aStructure and mechanism of haem-dependent nitrogen\u2013nitrogen bond formation in piperazate synthase<\/p>\n<p>\u539f\u6587\u4f5c\u8005\uff1aMelanie A. Higgins, Xinjie Shi, Jordi Soler, Jill B. Harland, Taylor Parkkila, Nicolai Lehnert, Marc Garcia-Borr\u00e0s, Yi-Ling Du &amp; Katherine S. Ryan<\/p>\n<p>https:\/\/doi.org\/10.1038\/s41929-024-01280-8<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u542b\u6709\u6c2e-\u6c2e\uff08N\u2013N\uff09\u952e\u7684\u5206\u5b50\u6db5\u76d6\u4e86\u591a\u79cd\u5b98\u80fd\u56e2\uff0c\u5305\u62ec\u80bc\u3001\u91cd\u6c2e\u5316\u5408\u7269\u3001\u5421\u5511\u548cN-\u4e9a\u785d\u57fa\u5316\u5408\u7269\u3002\u542bN\u2013N\u7684\u5206\u5b50\u662f\u6c2e\u5faa [&hellip;]<\/p>\n","protected":false},"author":326,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[14],"tags":[],"class_list":["post-53595","post","type-post","status-publish","format-standard","hentry","category-tuijianyuedu"],"_links":{"self":[{"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/posts\/53595","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/users\/326"}],"replies":[{"embeddable":true,"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/comments?post=53595"}],"version-history":[{"count":1,"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/posts\/53595\/revisions"}],"predecessor-version":[{"id":53596,"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/posts\/53595\/revisions\/53596"}],"wp:attachment":[{"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/media?parent=53595"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/categories?post=53595"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/tags?post=53595"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}