{"id":53493,"date":"2025-03-08T08:09:45","date_gmt":"2025-03-08T00:09:45","guid":{"rendered":"https:\/\/www.chemhui.com\/?p=53493"},"modified":"2025-02-27T10:11:28","modified_gmt":"2025-02-27T02:11:28","slug":"nat-chem-biol-trpm4%e7%9a%84%e6%8c%81%e7%bb%ad%e6%bf%80%e6%b4%bb%e8%a7%a6%e5%8f%91%e4%bb%a5%e9%92%a0%e8%bf%87%e8%bd%bd%e4%b8%ba%e7%89%b9%e5%be%81%e7%9a%84%e5%9d%8f%e6%ad%bb%e6%80%a7%e7%bb%86","status":"publish","type":"post","link":"http:\/\/www.chemhui.com\/nat-chem-biol-trpm4%e7%9a%84%e6%8c%81%e7%bb%ad%e6%bf%80%e6%b4%bb%e8%a7%a6%e5%8f%91%e4%bb%a5%e9%92%a0%e8%bf%87%e8%bd%bd%e4%b8%ba%e7%89%b9%e5%be%81%e7%9a%84%e5%9d%8f%e6%ad%bb%e6%80%a7%e7%bb%86\/","title":{"rendered":"Nat. Chem. Biol. | TRPM4\u7684\u6301\u7eed\u6fc0\u6d3b\u89e6\u53d1\u4ee5\u94a0\u8fc7\u8f7d\u4e3a\u7279\u5f81\u7684\u574f\u6b7b\u6027\u7ec6\u80de\u6b7b\u4ea1"},"content":{"rendered":"<p>\u5206\u4eab\u4e00\u7bc7\u53d1\u8868\u5728Nature Chemical Biology\u4e0a\u7684\u6587\u7ae0\uff0c\u9898\u76ee\u4e3a\u201cPersistent activation of TRPM4 triggers necrotic cell death characterized by sodium overload\u201d\uff0c\u901a\u8baf\u4f5c\u8005\u662f\u6765\u81ea\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u533b\u5b66\u9662\u7684\u949f\u6e05\u6559\u6388\u548c\u4e2d\u56fd\u79d1\u5b66\u9662\u4e0a\u6d77\u836f\u7269\u6240\u7684\u674e\u626c\u7814\u7a76\u5458\u3002<\/p>\n<section><img decoding=\"async\" title=\"1\" src=\"https:\/\/10110.seohost.cn\/storage\/10110\/article\/20250227\/1740622247117052.jpg\" alt=\"1\" 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