{"id":47855,"date":"2023-05-04T08:36:55","date_gmt":"2023-05-04T00:36:55","guid":{"rendered":"https:\/\/www.chemhui.com\/?p=47855"},"modified":"2023-04-19T10:39:30","modified_gmt":"2023-04-19T02:39:30","slug":"angew-chem-%ef%bc%9a%e7%82%94%e7%83%83%e6%a1%a5%e8%81%94c-h%e9%94%ae%e6%b4%bb%e5%8c%96-15-%e9%92%af%e8%bf%81%e7%a7%bb%e7%ad%96%e7%95%a5%e6%9e%84%e5%bb%ba%e8%8b%af%e5%b9%b6%e4%ba%8c","status":"publish","type":"post","link":"http:\/\/www.chemhui.com\/angew-chem-%ef%bc%9a%e7%82%94%e7%83%83%e6%a1%a5%e8%81%94c-h%e9%94%ae%e6%b4%bb%e5%8c%96-15-%e9%92%af%e8%bf%81%e7%a7%bb%e7%ad%96%e7%95%a5%e6%9e%84%e5%bb%ba%e8%8b%af%e5%b9%b6%e4%ba%8c\/","title":{"rendered":"Angew. Chem. \uff1a\u7094\u70c3\u6865\u8054C-H\u952e\u6d3b\u5316\u2014\u20141,5-\u94af\u8fc1\u79fb\u7b56\u7565\u6784\u5efa\u82ef\u5e76\u4e8c\u6c22\u544b\u5583\u548c\u82ef\u5e76\u5432\u54da\u5549\u7c7b\u5316\u5408\u7269"},"content":{"rendered":"<section>\n<section>\n<section>\n<section>\n<section>1,4-\u94af\/\u6c22\u8fc1\u79fb\u662f\u5b9e\u73b0\u8fdc\u7a0b\u9009\u62e9\u6027C-H\u952e\u6d3b\u5316\u7684\u91cd\u8981\u65b9\u6cd5\u3002\u5728\u524d\u671f\u7814\u7a76\u4e2d\uff0c\u6e56\u5357\u5e08\u8303\u5927\u5b66\u9ec4\u5b66\u826f\u8bfe\u9898\u7ec4\u53d1\u5c55\u4e86\u5361\u5bbe\u6865\u8054C-H\u952e\u6d3b\u5316\u53cd\u5e94\u7b56\u7565\uff08Carbene Bridging C-H Activation, CBA\uff09\u3002\u57fa\u4e8eCBA\u7b56\u7565\u53ef\u4ee5\u5b9e\u73b0\u5361\u5bbe\u8fc1\u79fb\u63d2\u5165\u4fc3\u8fdb\u76841,4-\u94af\/\u6c22\u8fc1\u79fb\u53cd\u5e94\uff0c\u53d1\u5c55\u4e86\u6784\u5efa\u4e86\u5f02\u9999\u8c46\u7d20\u3001\u4e03\u3001\u516b\u5143\u73af\u5185\u8102\u548c\u4e03\u5143\u73af\u5185\u9170\u80fa\u4ee5\u53ca\u82ef\u5e76\u5f02\u55b9\u5549\u916e\u7b49\u7c7b\u5316\u5408\u7269\u7684\u65b0\u65b9\u6cd5(<em>Angew. Chem. Int. Ed. 2018, 57, 319; Nat. Commun. 2020, 11, 461; Angew. Chem. Int. Ed.\u00a02020, 59, 18261; ACS Catal.\u00a02021, 11, 1570<\/em>)\u3002\u76f8\u8f83\u4e8e1,4-\u94af\/\u6c22\u8fc1\u79fb\u7684\u5e7f\u6cdb\u62a5\u9053\uff0c1,5-\u94af\u8fc1\u79fb\u7684\u62a5\u5bfc\u8f83\u5c11\uff0c\u7a76\u5176\u539f\u56e0\u53ef\u80fd\u5728\u4e8e\u5176\u8fc7\u6e21\u6001\u516d\u5143\u94af\u73af\u66f4\u5bb9\u6613\u53d1\u751f\u8fd8\u539f\u6d88\u9664\u5f97\u5230\u4e94\u5143\u73af\u4ea7\u7269\uff08\u56fe1-a\uff09\u3002\u57fa\u4e8e\u524d\u671f\u7814\u7a76\uff0c\u4f5c\u8005\u53d1\u5c55\u4e86\u7094\u70c3\u6865\u8054\u7684C-H\u952e\u6d3b\u5316\u7b56\u7565\uff08Alkyne Bridging C-H Activation\uff09\uff0c\u5b9e\u73b0\u4e86\u4ece\u70ef\u57fa\u81f3\u919b\u57fa\u78b3\u6c22\u952e\u76841,5-\u94af\/\u6c22\u8fc1\u79fb\u3002\u901a\u8fc7\u8be51,5-\u94af\/\u6c22\u8fc1\u79fb\u4e32\u8054\u8131\u7fb0\u82b3\u57fa\u5316\u3001\u8131\u7fb0\u70ef\u57fa\u5316\/\u8131\u7fb0\u7094\u57fa\u5316\u548c\u8131\u7fb0Catellani\u53cd\u5e94\uff0c\u4f5c\u8005\u53d1\u5c55\u4e86\u5408\u6210\u82ef\u5e76\u4e8c\u6c22\u544b\u5583\u548c\u82ef\u5e76\u5432\u54da\u5549\u884d\u751f\u7269\u7684\u65b0\u65b9\u6cd5\uff08\u56fe1-b\uff09\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p>&nbsp;<\/p>\n<section>\n<section><\/section>\n<\/section>\n<p>&nbsp;<\/p>\n<section><img decoding=\"async\" title=\"1\" src=\"http:\/\/9794.seohost.cn\/storage\/9794\/article\/20230406\/1680748569685295.png\" alt=\"1\" \/><\/section>\n<section>\u56fe1. 1,4-\u548c1,5-\u94af\/\u6c22\u8fc1\u79fb\u53cd\u5e94<\/p>\n<\/section>\n<section>\n<section>\n<section>\n<section>\n<section>\u7ecf\u8fc7\u7cfb\u7edf\u7684\u63a2\u7d22\u7814\u7a76\uff0c\u6700\u7ec8\u5b9e\u73b0\u4e861\uff0c5-\u94af\/\u6c22\u8fc1\u79fb\u4e32\u8054\u8131\u7fb0\u82b3\u57fa\u5316\u3001\u7094\u57fa\u5316\u548c\u5361\u5bbe\u5076\u8054\u70ef\u57fa\u5316\u7684\u4ea7\u7269\uff0c\u5e95\u7269\u9002\u7528\u8303\u56f4\u7684\u8003\u5bdf\u53d1\u73b0\uff0c\u5b98\u80fd\u56e2\u8010\u53d7\u6027\u8868\u73b0\u826f\u597d\u3002\u82b3\u57fa\u5316\u90e8\u5206\u82b3\u57fa\u787c\u9178\u3001\u6742\u73af\u787c\u9178\u4ee5\u53ca\u70ef\u70c3\u787c\u9178\u7b49\u591a\u79cd\u787c\u9178\u5747\u80fd\u4f5c\u4e3a\u5076\u8054\u8bd5\u5242\u53c2\u4e0e\u53cd\u5e94\uff1b\u540c\u6837\u7094\u57fa\u5316\u90e8\u5206\u542b\u82b3\u57fa\u4e0e\u70f7\u57fa\u53d6\u4ee3\u7684\u7094\u4e19\u9187\u5747\u9002\u7528\u4e8e\u6b64\u53cd\u5e94\u4f53\u7cfb\uff1b\u6b64\u5916\u5361\u5bbe\u524d\u4f53\u78fa\u9170\u8159\u4e5f\u5c55\u73b0\u4e86\u826f\u597d\u7684\u666e\u9002\u6027\uff08\u56fe 2\uff09\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section>\n<section><\/section>\n<\/section>\n<section><img decoding=\"async\" title=\"2\" src=\"http:\/\/9794.seohost.cn\/storage\/9794\/article\/20230406\/1680748578727332.png\" alt=\"2\" \/><\/section>\n<section>\u56fe2. \u5e95\u7269\u9002\u7528\u6027\u7814\u7a76<\/p>\n<\/section>\n<section>\n<section>\n<section>\n<section>\n<section>\u6b64\u5916\uff0c\u4f5c\u8005\u8fd8\u5c1d\u8bd5\u4e861,5-\u94af\/\u6c22\u8fc1\u79fb\u4e32\u8054\u8131\u7fb0Catellani\u578b\u53cd\u5e94\uff08\u56fe 3\uff09\uff0c\u5e76\u6210\u529f\u5b9e\u73b0\u919b\u57fa\u90bb\u4f4d\u6c28\u57fa\u5316\/\u8131\u7fb0\u7094\u57fa\u5316\u7684\u53cd\u5e94\uff1b\u62a5\u9053\u4e86\u9996\u4f8b\u57fa\u4e8e\u919b\u57fa\u7684\u8131\u7fb0Catellani\u53cd\u5e94\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section>\n<section><\/section>\n<\/section>\n<section><img decoding=\"async\" title=\"3\" src=\"http:\/\/9794.seohost.cn\/storage\/9794\/article\/20230406\/1680748586819702.png\" alt=\"3\" \/><\/section>\n<section>\u56fe 3. \u00a01,5-\u94af\u8fc1\u79fb\u4fc3\u8fdb\u919b\u57fa\u8131\u7fb0Catellani\u578b\u53cd\u5e94<\/p>\n<\/section>\n<section>\n<section>\n<section>\n<section>\n<section>\u673a\u7406\u5b9e\u9a8c\u7814\u7a76\u4e2d\uff0c\u4f5c\u8005\u901a\u8fc7CO\u7684\u6355\u6349\u5b9e\u9a8c\u8bc1\u660e\u4e86\u6b64\u53cd\u5e94\u7ecf\u5386\u4e86\u8131\u7fb0\u8fc7\u7a0b\uff08\u56fe 4A\uff09\uff0c\u5e76\u4e14\u901a\u8fc7\u5f53\u91cf\u5b9e\u9a8c\u83b7\u5f97\u4e86\u8131\u7fb0\u82b3\u57fa\u94af\u7269\u79cd\uff0c\u5355\u6676\u884d\u5c04\u8868\u5f81\u4e86\u5176\u7ed3\u6784\uff08\u56fe 4B\uff09\uff0c\u5229\u7528\u6c18\u4ee3\u5b9e\u9a8c\u4f50\u8bc1\u4e86\u94af\/\u6c22\u8fc1\u79fb\u5386\u7a0b\uff08\u56fe 4C\uff09\uff0c\u4e14\u540c\u65f6\u8868\u660e\u919b\u57fa\u7684\u78b3\u6c22\u952e\u6d3b\u5316\u5e76\u4e0d\u662f\u51b3\u901f\u6b65\u9aa4\uff08\u56fe 4D\uff09\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section>\n<section><\/section>\n<\/section>\n<section><img decoding=\"async\" title=\"4\" src=\"http:\/\/9794.seohost.cn\/storage\/9794\/article\/20230406\/1680748594944578.png\" alt=\"4\" \/><\/section>\n<section>\u56fe 4 \u673a\u7406\u7814\u7a76<\/p>\n<\/section>\n<section>\n<section>\n<section>\n<section>\n<section>\u4e2d\u56fd\u79d1\u5b66\u9662\u5927\u5b66\u6c6a\u5fd7\u7965\u6559\u6388\u8bfe\u9898\u7ec4\u5bf9\u94af\u8fc1\u79fb\u5386\u7a0b\u8fdb\u884c\u4e86DFT\u8ba1\u7b97\uff08\u56fe5\uff09\uff0c\u5e76\u63d0\u51fa\u4e86\u7ecfPd(IV)\u4e2d\u95f4\u4f53\u7684\u5206\u6b65\u8fc1\u79fb\u53cd\u5e94\u673a\u7406\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section>\n<section><\/section>\n<\/section>\n<section><img decoding=\"async\" title=\"7\" src=\"http:\/\/9794.seohost.cn\/storage\/9794\/article\/20230406\/1680748609275574.png\" alt=\"7\" \/><\/section>\n<section>\u56fe5. DFT\u8ba1\u7b97<\/p>\n<\/section>\n<section>\n<section>\n<section>\n<section><strong>\u8bba<\/strong><strong>\u6587\u4fe1\u606f<\/strong><\/p>\n<\/section>\n<\/section>\n<section>\n<section><\/section>\n<\/section>\n<section>\n<section>\n<section>\n<section>\n<section><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section>Alkyne Insertion Enabled Vinyl to Acyl 1,5-Palladium Migration: Rapid Access to Substituted 5-Membered-Dihydrobenzofurans and Indolines<\/p>\n<p>Dr. Mingruo Ding,\u00a0Pengcheng Ou,\u00a0Xuening Li,\u00a0Yinghua Yu,\u00a0Mengmeng Niu,\u00a0Yongjian Yang,\u00a0Yewei Huang,\u00a0Prof.\u2005Dr. Zhi-Xiang Wang,\u00a0Prof.\u2005Dr. Xueliang Huang<\/p>\n<p><em>Angewandte Chemie International Edition<\/em><\/p>\n<p>DOI:\u00a010.1002\/anie.202300703<\/p>\n<\/section>\n<\/section>\n<\/section>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>1,4-\u94af\/\u6c22\u8fc1\u79fb\u662f\u5b9e\u73b0\u8fdc\u7a0b\u9009\u62e9\u6027C-H\u952e\u6d3b\u5316\u7684\u91cd\u8981\u65b9\u6cd5\u3002\u5728\u524d\u671f\u7814\u7a76\u4e2d\uff0c\u6e56\u5357\u5e08\u8303\u5927\u5b66\u9ec4\u5b66\u826f\u8bfe\u9898\u7ec4\u53d1\u5c55\u4e86\u5361\u5bbe\u6865\u8054 [&hellip;]<\/p>\n","protected":false},"author":326,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[14],"tags":[],"class_list":["post-47855","post","type-post","status-publish","format-standard","hentry","category-tuijianyuedu"],"_links":{"self":[{"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/posts\/47855","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/users\/326"}],"replies":[{"embeddable":true,"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/comments?post=47855"}],"version-history":[{"count":1,"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/posts\/47855\/revisions"}],"predecessor-version":[{"id":47856,"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/posts\/47855\/revisions\/47856"}],"wp:attachment":[{"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/media?parent=47855"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/categories?post=47855"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.chemhui.com\/wp-json\/wp\/v2\/tags?post=47855"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}